Brachial Artery Thrombosis in an 8-year-old Boy with Antiphospholipid Antibodies Induced by Mycoplasma pneumoniae Infection: a Case Report

Author: Jung Hee WOO ¹ ; Jung Hyun KWON ; Bo Kyung JE ; Jae Seoung SHIN ; Won Hee SEO ; Gi Young JANG
Author Information

1. Department of Pediatrics, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, the Republic of Korea. wonny508@korea.ac.kr
Publication Type:Case Report
Keywords: Mycoplasma pneumoniae; Antiphospholipid antibodies; Thrombus
MeSH: Antibodies, Antiphospholipid; Autoimmune Diseases; Brachial Artery; Child; Humans; Male; Mycoplasma pneumoniae; Mycoplasma; Pneumonia; Pneumonia, Mycoplasma; Protein S; Thrombectomy; Thrombosis
From:Pediatric Infection & Vaccine 2019;26(1):60-65
CountryRepublic of Korea
Language:English
Abstract: Antiphospholipid antibodies may be produced in cases involving autoimmune diseases and can sometimes be caused by infections, such as Mycoplasma pneumoniae infection. However, antiphospholipid antibodies causing thrombosis associated with M. pneumoniae pneumonia in children have rarely been reported. We report a case of an 8-year-old boy with M. pneumoniae pneumonia with antiphospholipid antibodies, complicated by brachial artery thrombosis. He was found to have antiphospholipid antibodies and low protein S levels. The brachial artery thrombus was removed via thrombectomy. The titers of antiphospholipid antibodies turned normal within 5 months. This is a rare case of M. pneumoniae infection with brachial artery thrombosis associated with transient antiphospholipid antibodies.