A Child of Severe Mycoplasma pneumoniae pneumonia with Multiple Organ Failure Treated with ECMO and CRRT
- Author:
Woojin HWANG
1
;
Yoonjin LEE
;
Eunjee LEE
;
Jiwon M LEE
;
Hong Ryang KIL
;
Jae Hyeon YU
;
Eun Hee CHUNG
Author Information
- Publication Type:Case Report
- Keywords: Mycoplasma pneumoniae; Pneumonia; Acute respiratory distress syndrome; Extracorporeal membrane oxygenation; Renal replacement therapy
- MeSH: Autistic Disorder; Child; Clarithromycin; Cough; Dyspnea; Extracorporeal Membrane Oxygenation; Fever; Hepatitis; Hospitalization; Humans; Immunoglobulin G; Immunoglobulins; Intensive Care Units; Korea; Lethargy; Leukocytosis; Male; Multiple Organ Failure; Mycoplasma pneumoniae; Mycoplasma; Oxygen; Pleural Effusion; Pneumonia; Pneumonia, Mycoplasma; Polymerase Chain Reaction; Radiography; Renal Replacement Therapy; Respiratory Distress Syndrome, Adult; Sputum; Thorax
- From:Pediatric Infection & Vaccine 2019;26(1):71-79
- CountryRepublic of Korea
- Language:English
- Abstract: Mycoplasma pneumoniae (MP) is the most common causative agent of community-acquired pneumonia in school-aged children. An 8-year-old boy who had been diagnosed with autism looked severely ill when he presented to our hospital due to dyspnea and lethargy. He had fever and cough 7 days prior to hospitalization. He had signs and symptoms of severe respiratory distress. The percutaneous oxygen saturation was 88% at high oxygen supply. Chest radiography showed diffusely increased opacity with moderate pleural effusion. He was intubated immediately and admitted to the intensive care unit. Under the clinical impression of mycoplasmal pneumonia, intravenous clarithromycin was started. Laboratory findings showed leukocytosis, hepatitis, decreased renal function, and presence of serum MP immunoglobulin (Ig) M (+) IgG (+) and sputum MP polymerase chain reaction (+). On hospital day 2, the patient developed multiple organ failure with acute respiratory distress syndrome (ARDS). Veno-venous extracorporeal membrane oxygenation (ECMO) was performed with continuous renal replacement therapy (CRRT) and was weaned successfully. This is the first reported case of an ARDS due to MP infection complicated by multiple organ failure that was successfully treated with ECMO and CRRT in South Korea.