A rare case of ovarian vein thrombosis in a gestational trophoblastic neoplasia patient
10.5468/ogs.2019.62.3.190
- Author:
In Young KIM
1
;
Seung Hyun KIM
;
In Taek HWANG
;
Joong Gyu HA
;
Jae Ho CHA
Author Information
1. Department of Obstetrics and Gynecology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea. medicine00@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Gestational trophoblastic neoplasia;
Venous thrombosis;
Anticoagulants
- MeSH:
Abdominal Pain;
Amenorrhea;
Anticoagulants;
Diagnosis;
Diagnosis, Differential;
Disease Progression;
Drug Therapy;
Female;
Fever;
Follow-Up Studies;
Gestational Trophoblastic Disease;
Humans;
Hydatidiform Mole;
Leukocytosis;
Methotrexate;
Pregnancy;
Rare Diseases;
Recurrence;
Thrombosis;
Veins;
Venous Thrombosis;
Young Adult
- From:Obstetrics & Gynecology Science
2019;62(3):190-193
- CountryRepublic of Korea
- Language:English
-
Abstract:
Ovarian vein thrombosis (OVT) is a rare disease with complications that can be life-threatening. An ovarian vein thrombus in a gestational trophoblastic neoplasia (GTN) is an extremely rare condition that has not been previously reported in the literature. We report the case of a 23-year-old woman who presented with symptoms of amenorrhea for 15 weeks and 6 days along with intermittent lower abdominal pain. She was diagnosed with a hydatidiform mole, and a metastatic workup was scheduled. Abdominal computed tomography showed a right ovarian vein thrombus. She received methotrexate chemotherapy combined with oral anticoagulants. Complete radiological remission was obtained. During the 12-month follow-up period, no disease progression or recurrence was noted. Early recognition and detection of the condition are of the utmost importance. The differential diagnosis of OVT must be considered when there is unexplained abdominal pain, fever, and leukocytosis during the diagnosis and treatment of GTN. A high level of suspicion is required for prompt diagnosis of OVT.
