Bilateral Acute Retinal Necrosis and Encephalomalacia Due to Herpes Simplex Virus Infection in a Premature Infant
- Author:
Mi Hye BAE
1
;
Na Rae LEE
;
Young Mi HAN
;
Lira YOON
;
Young Mi KIM
;
Shin Yun BYUN
;
Jae Jung LEE
;
Han Jo KWON
;
Min Jung KWAK
;
Kyung Hee PARK
Author Information
- Publication Type:Case Report
- Keywords: Herpesvirus 2, human; Retinal necrosis syndrome, acute; Infant, premature
- MeSH: Body Weight; Encephalitis; Encephalomalacia; Exudates and Transudates; Female; Herpes Simplex; Herpesvirus 2, Human; Humans; Infant; Infant, Newborn; Infant, Premature; Necrosis; Parturition; Pregnancy; Retinal Necrosis Syndrome, Acute; Retinal Vasculitis; Retinaldehyde; Simplexvirus; Skin; Uveitis
- From:Neonatal Medicine 2019;26(1):63-66
- CountryRepublic of Korea
- Language:English
- Abstract: Herpes simplex virus (HSV) is a common pathogen, that causes a broad spectrum of diseases, ranging from minor skin infections to severe encephalitis and widespread infections. Acute retinal necrosis (ARN), one of the most serious manifestations of HSV infection, is defined as a rapidly progressing necrotizing retinopathy that presents discrete areas of circumferential retinal necrosis, along with signs of uveitis, vitreitis, and retinal vasculitis. We encountered a case of a female infant, born at 33 weeks of gestation with a body weight at birth of 2,080 g, who had ARN and encephalomalacia due to HSV infection. ARN associated with HSV infection should be suspected when nonspecific retinal exudates are observed in neonates, especially preterm infants.
