Determination of Silybin B in the Different Parts of Silybum marianum using HPLC-UV
10.20307/nps.2018.24.2.82
- Author:
Joyce P RODRIGUEZ
1
;
Norman G QUILANTANG
;
Ju Sung LEE
;
Jeong Min LEE
;
Hyun Young KIM
;
Jae Suk SHIM
;
Sanghyun LEE
Author Information
1. Department of Integrative Plant Science, Chung-Ang University, Anseong 17546, Korea. slee@cau.ac.kr
- Publication Type:Original Article
- Keywords:
HPLC-UV;
Silybum marianum;
silybin B;
silymarin
- MeSH:
Flavonoids;
Milk Thistle;
Polyphenols;
Silymarin
- From:Natural Product Sciences
2018;24(2):82-87
- CountryRepublic of Korea
- Language:English
-
Abstract:
Silymarin is the standardized extract from Silybum marianum which consists mainly of flavonoids and polyphenols. It is highly regarded for its hepatoprotective ability. Silybin B is a flavonolignan and one of the active components of silymarin. The content of silybin B in various parts of S. marianum was analyzed by HPLC-UV. Results show that the extract of seeds contain the highest amount of silybin B (7.434 mg/g DW). The petioles of S. marianum showed a low content of silybin B. This study revealed that seeds of S. marianum contain high amount of silybin B and could be a good source of the compound.