The effect of botulinum toxin-A injection into the masseter muscles on prevention of plate fracture and post-operative relapse in patients receiving orthognathic surgery
10.1186/s40902-018-0174-0
- Author:
Sung Ho SHIN
1
;
Yei Jin KANG
;
Seong Gon KIM
Author Information
1. Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Jukheon gil 7, Gangneung, Gangwondo 25457, Republic of Korea. kimsg@gwnu.ac.kr
- Publication Type:Original Article
- Keywords:
Botulinum toxins;
Type A;
Fracture fixation;
Internal;
Osteotomy;
Sagittal split ramus;
Postoperative complications
- MeSH:
Botulinum Toxins;
Fracture Fixation;
Genioplasty;
Humans;
Incidence;
Masseter Muscle;
Orthognathic Surgery;
Osteotomy;
Osteotomy, Sagittal Split Ramus;
Postoperative Complications;
Recurrence
- From:Maxillofacial Plastic and Reconstructive Surgery
2018;40(1):36-
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Botulinum toxin-A (BTX-A) injection into muscle reduces muscular power and may prevent post-operative complication after orthognathic surgery. The purpose of this study was (1) to evaluate BTX-A injection into the masseter muscle on the prevention of plate fracture and (2) to compare post-operative relapse between the BTX-A injection group and the no injection group. METHODS: Sixteen patients were included in this study. Eight patients received BTX-A injection bilaterally, and eight patients served as control. All patients received bilateral sagittal split ramus osteotomy for the mandibular setback and additional surgery, such as LeFort I osteotomy or genioplasty. Post-operative plate fracture was recorded. SNB angle, mandibular plane angle, and gonial angle were used for post-operative relapse. RESULTS: Total number of fractured plates in patients was 2 out of 16 plates in the BTX-A injection group and that was 8 out of 16 plates in the no treatment group (P = 0.031). However, there were no significant differences in post-operative changes in SNB angle, mandibular plane angle, and gonial angle between groups (P > 0.05). CONCLUSIONS: BTX-A injection into the masseter muscle could reduce the incidence of plate fracture.
