Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016–2017
10.14405/kjvr.2018.58.3.143
- Author:
Kiju KIM
1
;
Jong Young CHOI
;
Kwang Soo LYOO
;
Tae Wook HAHN
Author Information
1. College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea. twhahn@kangwon.ac.kr
- Publication Type:Brief Communication
- Keywords:
capsid proteins;
genetic variation;
phylogenetic analysis;
porcine circovirus type 2
- MeSH:
Capsid Proteins;
Circovirus;
Epidemiology;
Genetic Variation;
Genotype;
Glycine;
Korea;
Open Reading Frames;
Population Characteristics
- From:Korean Journal of Veterinary Research
2018;58(3):143-146
- CountryRepublic of Korea
- Language:English
-
Abstract:
The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016–2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3–100% homology at the nucleotide (deduced amino acid 86.3–100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea.
