Detection and characterization of avian hepatitis E virus from broiler breeders and layers in Korea
10.14405/kjvr.2018.58.1.45
- Author:
Hyun Woo MOON
1
;
Haan Woo SUNG
;
Hyuk Moo KWON
Author Information
1. Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea. kwonhm@kangwon.ac.kr
- Publication Type:Brief Communication
- Keywords:
avian hepatitis E virus;
helicase gene;
hypervariable region;
sequences
- MeSH:
Agriculture;
Base Sequence;
Genotype;
Hepevirus;
Korea;
Trees
- From:Korean Journal of Veterinary Research
2018;58(1):45-49
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The helicase genes and hypervariable regions (HVRs) of three avian hepatitis E viruses (HEVs) detected at three different farms were sequenced and characterized. Two isolates (DW-L and GI-B2) were classified as genotype 2 and one isolate (GR-B) was classified as genotype 1. A phylogenetic tree, based on the helicase gene and HVR nucleotide sequences, revealed the newly detected viruses and other avian HEVs were classified similarly. Unlike previously reported avian HEVs, the DW-L isolate detected in broiler breeders with characteristic lesions of avian HEV had no prolinerich motif in its HVR, suggesting that the proline-rich motif is non-essential for viral replication and infection.
