Clinical and MRI Characteristics of Uterine Cervical Adenocarcinoma: Its Variants and Mimics
- Author:
Tsukasa SAIDA
1
;
Akiko SAKATA
;
Yumiko Oishi TANAKA
;
Hiroyuki OCHI
;
Toshitaka ISHIGURO
;
Masafumi SAKAI
;
Hiroaki TAKAHASHI
;
Toyomi SATOH
;
Manabu MINAMI
Author Information
- Publication Type:Review
- Keywords: Uterus; Cervical cancer; Adenocarcinoma; MRI; Human papillomavirus
- MeSH: Adenocarcinoma; Adenocarcinoma, Mucinous; Carcinoma, Squamous Cell; Diagnosis; Humans; Hyperplasia; Magnetic Resonance Imaging; Mass Screening; Prognosis; Uterine Cervical Neoplasms; Uterus
- From:Korean Journal of Radiology 2019;20(3):364-377
- CountryRepublic of Korea
- Language:English
- Abstract: Adenocarcinoma currently accounts for 10–25% of all uterine cervical carcinomas and has a variety of histopathological subtypes. Among them, mucinous carcinoma gastric type is not associated with high-risk human papillomavirus (HPV) infection and a poor prognosis, while villoglandular carcinoma has an association with high-risk HPV infection and a good prognosis. They show relatively characteristic imaging findings which can be suggested by magnetic resonance imaging (MRI), though the former is sometimes difficult to be distinguished from lobular endocervical glandular hyperplasia. Various kinds of other tumors including squamous cell carcinoma should be also differentiated on MRI, while it is currently difficult to distinguish them on MRI, and HPV screening and pathological confirmation are usually necessary for definite diagnosis and further patient management.
