Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma
- Author:
Swati SHARMA
1
;
Monica MEHENDIRATTA
;
Nivedita CHAUDHARY
;
Vineet GUPTA
;
Maulshree KOHLI
;
Anjana ARORA
Author Information
- Publication Type:Case Report
- Keywords: Squamous metaplasia; Pleomorphic adenoma; Pathology
- MeSH: Adenoma, Pleomorphic; Diagnostic Errors; Female; Humans; Medical Overuse; Metaplasia; Middle Aged; Palate; Pathology; Salivary Glands
- From:Journal of Pathology and Translational Medicine 2018;52(6):411-415
- CountryRepublic of Korea
- Language:English
- Abstract: Pleomorphic adenoma (PA) is the most common benign salivary gland tumor. Histologically, squamous metaplasia has been reported in PA, but has rarely been documented as being extensive enough to cause significant misdiagnosis. Here, we present an unusual case of PA in a 50-year-old female patient presenting with swelling on the postero-lateral aspect of the palate for a week. Histopathologically, the tumor exhibited the features of conventional PA with extensive squamous metaplasia and giant keratotic lamellae in cyst-like areas. Such exuberant squamous metaplasia and keratin can be a diagnostic and prognostic pitfall and lead to overtreatment of the patient.
