Importance of Individual Ghost Cells in Fine-Needle Aspiration Cytology Diagnosis of Pilomatricoma
- Author:
Kanghee HAN
1
;
Hwa Jeong HA
;
Joon Seog KONG
;
Jae Kyung MYUNG
;
Sunhoo PARK
;
Jung Soon KIM
;
Myung Soon SHIN
;
Hye Sil SEOL
;
Jae Soo KOH
;
Seung Sook LEE
Author Information
- Publication Type:Original Article
- Keywords: Pilomatricoma; Fine-needle aspiration cytology; Ghost cells
- MeSH: Biopsy, Fine-Needle; Diagnosis; Diagnostic Errors; Korea; Pilomatrixoma
- From:Journal of Pathology and Translational Medicine 2018;52(1):45-50
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Although histological diagnosis of pilomatricoma is not difficult because of its unique histological features, cytological diagnosis through fine-needle aspiration cytology (FNAC) is often problematic due to misdiagnoses as malignancy. METHODS: We reviewed the cytological features of 14 cases of histologically-proven pilomatricoma from Korea Cancer Center Hospital, with a discussion on the diagnostic pitfalls of FNAC. RESULTS: Among 14 cases of pilomatricoma, 10 (71.4%) were correctly diagnosed through FNAC, and two (14.3%) were misdiagnosed as carcinoma. Cytologically, all cases had easily recognizable clusters of basaloid cells and foreign body-type multinucleated cells. Although ghost cells were also found in all cases, some were inconspicuous and hardly recognizable due to their small numbers. CONCLUSIONS: An accurate diagnosis of pilomatricoma in FNAC is feasible with consideration of clinical information and close examination of ghost cells.
