Treatment of Severe Small Bowel Involvement in Henoch-Schonlein Purpura: Two Cases Report.
- Author:
Hyung Tae KIM
1
;
Jin Soo MOON
;
Hyun Oh JANG
;
Heui Seung JO
;
Jong Guk LEE
;
Ki Hong KIM
;
Jung Wook SEO
;
Min Kyung KIM
Author Information
1. Department of Pediatrics, Ilsan Paik Hospital, College of Medicine, Inje University, Ilsan, Korea. jsmoon@ilsanpaik.ac.kr
- Publication Type:Case Report
- Keywords:
Henoch-Schonlein Purpura;
Immunoglobulin;
Infarction;
Small bowel;
Surgical intervention
- MeSH:
Abdominal Pain;
Humans;
Immunization, Passive;
Immunoglobulins;
Infarction;
Intussusception;
Joints;
Kidney;
Purpura, Schoenlein-Henoch*;
Skin;
Vasculitis
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2004;7(1):78-82
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Henoch-Schonlein purpura (HSP) is a vasculitis of the small vessels in skin, joints, gastrointestinal (GI) tract and kidney. GI symptoms occur in up to 85% of patients and may lead to severe problems such as intussusception, obstruction, and perforation. GI symptoms may not be easily controlled, showing refractoriness to the conventional corticosteroid therapy. Although GI involvements of HSP are acute, and self-limited in most instances, they may cause fatal results in some unusual cases. In such conditions all the possible therapeutic modalities should be considered. We report two cases of severe small bowel involvement of HSP. One case presented with severe abdominal pain showing refractoriness to corticosteroid, but improved with IV immunoglobulin therapy. In the second case, HSP with transmural infarction in the small bowel could be cured with surgical intervention.
