Cytomegalovirus-induced Childhood Menetrier's Disease with Peripheral Eosinophilia.
- Author:
Won Joung CHOI
1
;
Bo Young LEE
;
Hee Jung LEE
;
Hoon Kyu OH
;
Jin Bok HWANG
Author Information
1. Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea. pedgi@korea.com
- Publication Type:Case Report
- Keywords:
Menetrier's disease;
Cytomegalovirus;
Eosinophilia
- MeSH:
Abdominal Pain;
Child, Preschool;
Cytomegalovirus;
Cytomegalovirus Infections;
Edema;
Eosinophilia*;
Eosinophils;
Gastric Fundus;
Gastritis, Hypertrophic*;
Gastroenteritis;
Gelatin;
Humans;
Hyperplasia;
Hypertrophy;
Hypoalbuminemia;
Male;
Polymerase Chain Reaction;
Vomiting
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2004;7(1):87-91
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Herein, the case of a 5-year-old boy with cytomegalovirus-induced Menetrier's disease, with peripheral eosinophilia, presenting with abdominal pain and vomiting, followed by generalized edema, is reported. The initial laboratory findings, hypoalbuminemia and peripheral eosinophilia were noted, with no evidence of renal, hepatic, cardiac or allergic diseases. Gastrofiberscopy was performed under the suspicion of eosinophilic gastroenteritis with protein losing gastropathy. The gastrofiberscopy showed the characteristic features of giant hypertrophy of the gastric rugae, with large quantities of adherent gelatinous material on the gastric fundus and body. The histological findings revealed foveolar hyperplasia, compatible with Menetrier's disease, with massive eosinophilic infiltrations. The presence of cytomegalovirus infection was identified by serology and confirmed by urine PCR. His symptoms, gastrofiberscopic findings and peripheral eosinophilia resolved spontaneously, and he has remained well for 10 months.
