A Case of Long-Segment Barrett's Esophagus with Mixed Connective Tissue Disease
- Author:
Jun Il MUN
1
;
Dong Hoon KIM
;
Jee Hoon KOO
;
In Sung KIM
;
Kwang Jae LEE
Author Information
1. Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea. kjleemd@hotmail.com
- Publication Type:Case Report
- Keywords:
Barrett's esophagus;
Scleroderma;
Systemic;
Mixed connective tissue disease
- MeSH:
Adenocarcinoma;
Barrett Esophagus;
Epithelium;
Esophagus;
Female;
Gastroesophageal Reflux;
Goblet Cells;
Humans;
Korea;
Lupus Erythematosus, Systemic;
Metaplasia;
Mixed Connective Tissue Disease;
Polymyositis;
Prevalence;
Risk Factors;
Scleroderma, Systemic
- From:Korean Journal of Medicine
2012;82(1):73-77
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Barrett's esophagus is a metaplasia of the esophageal epithelium of any length, such that normal squamous epithelium is replaced by specialized columnar epithelium with goblet cells. It is important to diagnose and survey Barrett's esophagus because it is believed to be the major risk factor for development of esophageal adenocarcinoma. However, the prevalence of Barrett's esophagus in Korea is low. Mixed connective tissue disease (MCTD) is a systemic disorder in which patients have combinations of the clinical features of systemic lupus erythematosus, systemic sclerosis, and polymyositis. Although gastroesophageal reflux disease is common in esophageal involvement in MCTD, long-segment Barrett's esophagus in MCTD has not been reported in Korea. We report here a 15 cm-long segment of Barrett's esophagus extending to the proximal esophagus in a female patient who has had MCTD for 2 years, and we review the literature.
