F-18 Fluorodeoxyglucose PET/CT and Post Hoc PET/MRI in a Case of Primary Meningeal Melanomatosis.
10.3348/kjr.2013.14.2.343
- Author:
Hong Je LEE
1
;
Byeong Cheol AHN
;
Seong Wook HWANG
;
Suk Kyong CHO
;
Hae Won KIM
;
Sang Woo LEE
;
Jeong Hyun HWANG
;
Jaetae LEE
Author Information
1. Department of Nuclear Medicine, Dongnam Institute of Radiological & Medical Sciences (DIRAMS), Busan 619-953, Korea.
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Meningeal melanomatosis;
F-18 FDG;
PET/CT;
post hoc PET/MRI
- MeSH:
Adolescent;
Brain Neoplasms/*diagnosis/radionuclide imaging;
Fluorodeoxyglucose F18/diagnostic use;
Humans;
*Magnetic Resonance Imaging;
Male;
Melanoma/*diagnosis/radionuclide imaging;
Meningeal Neoplasms/*diagnosis/radionuclide imaging;
*Positron-Emission Tomography and Computed Tomography;
Radiopharmaceuticals/diagnostic use;
Whole Body Imaging
- From:Korean Journal of Radiology
2013;14(2):343-349
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary meningeal melanomatosis is a rare, aggressive variant of primary malignant melanoma of the central nervous system, which arises from melanocytes within the leptomeninges and carries a poor prognosis. We report a case of primary meningeal melanomatosis in a 17-year-old man, which was diagnosed with 18F-fluorodeoxyglucose (F-18 FDG) PET/CT, and post hoc F-18 FDG PET/MRI fusion images. Whole-body F-18 FDG PET/CT was helpful in ruling out the extracranial origin of melanoma lesions, and in assessing the therapeutic response. Post hoc PET/MRI fusion images facilitated the correlation between PET and MRI images and demonstrated the hypermetabolic lesions more accurately than the unenhanced PET/CT images. Whole body F-18 FDG PET/CT and post hoc PET/MRI images might help clinicians determine the best therapeutic strategy for patients with primary meningeal melanomatosis.
