A case of mixed prolactin and growth hormone-secreting pituitary microadenoma presenting galactorrhea.
- Author:
Myoung Beom KOH
1
;
Jae Han PARK
;
Yong Wan PARK
;
Sang Ah CHANG
;
Ki Ouk MIN
;
Eun Joo SEO
;
Ho Young SON
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. sangah@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Galactorrhea;
Acromegaly;
Pituitary neoplasm
- MeSH:
Acromegaly;
Adult;
Chemistry;
Extremities;
Female;
Galactorrhea*;
Glucose;
Hematology;
Humans;
Immunohistochemistry;
Magnetic Resonance Imaging;
Outpatients;
Pituitary Neoplasms;
Pregnancy;
Prolactin*;
Thyroid Gland
- From:Korean Journal of Medicine
2003;64(6):690-694
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of galactorrhea with acromegaly from the mixed prolactin and GH secreting pituitary microadenoma managed with a successful surgical complete removal. A 31-year-old woman visited our hospital complaining galactorrhea for more than 6 months after delivery. The physical findings of the patient were a prominent galactorrhea and mild acromegalic features of face and extremities. The laboratory findings of hematology and blood chemistry were normal. In addition, the basal levels of prolactin and GH were slightly elevated. The thyroid is in euthyroid state. The results of the combined anterior pituitary hormone-stimulation tests were that the prolactin and GH responses were stimulated exaggeratedly and the other hormonal ones were normal responses. The oral glucose loading test for acromegaly revealed non-responder results. The sellar MRI showed the 6 X 5 mm-sized pituitary microadenoma. She was operated for surgical removal of the lesions of which the immunohistochemistry findings were consistent with the positive findings for both prolactin and GH. She discharged without post-operative complication and has done well with normalized hormonal levels at outpatient department.
