Pelvic Floor Symptom Related Distress in Chronic Constipation Correlates With a Diagnosis of Irritable Bowel Syndrome With Constipation and Constipation Severity but Not Pelvic Floor Dyssynergia
- Author:
Prashant SINGH
1
;
Yoonjin SEO
;
Sarah BALLOU
;
Andrew LUDWIG
;
William HIRSCH
;
Vikram RANGAN
;
Johanna ITURRINO
;
Anthony LEMBO
;
Judy W NEE
Author Information
- Publication Type:Original Article
- Keywords: Constipation; Defecation; Lower urinary tract symptoms; Manometry; Pelvic floor
- MeSH: Abdominal Pain; Arm; Ataxia; Constipation; Defecation; Diagnosis; Humans; Irritable Bowel Syndrome; Lower Urinary Tract Symptoms; Manometry; Pelvic Floor; Pelvic Organ Prolapse; Retrospective Studies
- From:Journal of Neurogastroenterology and Motility 2019;25(1):129-136
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: Although symptoms related to the pelvic floor, such as pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTS), are common in patients with chronic constipation (CC), its impact is not clear. Our aims were to investigate the following (1) compare pelvic floor symptom related dysfunction in irritable bowel syndrome with constipation (IBS-C) and functional constipation (FC), and (2) symptom correlation with findings on anorectal manometry (ARM) and balloon expulsion test. METHODS: This was a retrospective analysis of patients with CC undergoing ARM. IBS-C and FC were diagnosed by Rome III criteria. Pelvic Floor Distress Inventory (PFDI-20) was used to measure pelvic floor symptom distress. Constipation Severity Scale was used to assess constipation severity. RESULTS: A total of 107 patients underwent ARM (64 FC, 43 IBS-C). The overall PFDI-20 score in IBS-C was higher compared with FC patients (118.0 vs 79.2, P = 0.001). In those with IBS-C, POP, LUTS, and colorectal symptoms subscales were all higher compared with FC patients (P < 0.05 for each). On multivariable regression, IBS-C (P = 0.001) and higher constipation severity (P = 0.001) were both independently associated with higher PFDI scores. ARM parameters and abnormal balloon expulsion test did not correlate with PFDI scores. CONCLUSIONS: Compared with FC patients, those with IBS-C have significantly higher distress from pelvic floor specific symptoms including POP and LUTS. Higher abdominal pain among IBS-C patients did not entirely explain these findings. A diagnosis of IBS-C and higher constipation severity correlated with PFDI-20 scores, but dyssynergia did not.
