Dietary effect of Lactobacillus plantarum CJLP55 isolated from kimchi on skin pH and its related biomarker levels in adult subjects
10.4163/jnh.2019.52.2.149
- Author:
Sangshin HAN
1
;
Jihye SHIN
;
Sunhee LIM
;
Hee Yoon AHN
;
Bongjoon KIM
;
Yunhi CHO
Author Information
1. Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Gyeonggi 17104, Korea. choyunhi@khu.ac.kr
- Publication Type:Randomized Controlled Trial
- Keywords:
skin pH;
Lactobacillus plantarum;
lactate;
free amino acid;
free fatty acid
- MeSH:
Adult;
Amino Acids;
Dietary Supplements;
Fatty Acids, Nonesterified;
Hand;
Humans;
Hydrogen-Ion Concentration;
Lactic Acid;
Lactobacillus plantarum;
Lactobacillus;
Oleic Acid;
Palmitic Acid;
Skin
- From:Journal of Nutrition and Health
2019;52(2):149-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The skin pH is maintained by epidermal lactate, free fatty acids (FFAs), and free amino acids (FAAs). As a significant determinant of skin health, the skin pH is increased (less acidic) under abnormal and aged skin conditions. In a search for dietary alternatives that would promote an acidic skin pH, this study investigated the dietary effects of Lactobacillus plantarum CJLP55 isolated from Korean kimchi on the skin pH, and epidermal levels of lactate, FFAs, and FAAs in adult subjects. METHODS: Seventy eight subjects (mean age 24.9 ± 0.5 years, range 19 ~ 37 years) were assigned randomly to ingest CJLP55, Lactobacillus strain from kimchi, (n = 39, CJLP group) or placebo supplements (n = 39, placebo group) for 12 weeks in a double-blind, placebo-controlled trial. Skin pH and epidermal levels of lactate, FFAs and FFAs were assessed at 0, 6 and 12 weeks. RESULTS: Although significant decreases in skin pH were observed in both the CJLP and placebo groups at 6 weeks, the skin pH was decreased significantly only in the CJLP group at 12 weeks. In parallel, the epidermal level of lactate in the CJLP group was also increased by 25.6% at 12 weeks. On the other hand, the epidermal level of FAAs were not altered in the CJLP and placebo groups, but the epidermal level of total FFAs, including palmitic acid and stearic acid, was lower in the CJLP group than in the placebo group over 12 weeks. The changes in the other FFAs, such as palmitoleic acid and oleic acid, were similar in the CJLP and placebo groups over 12 weeks. CONCLUSION: Overall, a dietary supplement of CJLP55 promotes acidic skin pH with a selective increase in epidermal lactate in adult subjects.
