Sequential Bilateral Rapid Destructive Inflammatory Coxarthrosis in a Patient with Human Immunodeficiency Virus
- Author:
Hyeon Jun KIM
1
;
Sung Soo KIM
;
Su Jin KIM
;
Kyung Ho LEE
Author Information
- Publication Type:Case Report
- Keywords: Femur head; Osteonecrosis; Rapidly destructive coxarthrosis; Human immunodeficiency virus
- MeSH: Arthroplasty, Replacement, Hip; Biopsy; Diagnosis; Female; Femur Head; Fibrosis; Head; Hip; Hip Joint; HIV; Humans; Humans; Inflammation; Osteoarthritis, Hip; Osteolysis; Osteonecrosis; Protease Inhibitors; RNA-Directed DNA Polymerase
- From:Hip & Pelvis 2018;30(2):115-119
- CountryRepublic of Korea
- Language:English
- Abstract: The diagnostic criteria for sequential rapidly destructive coxarthrosis remain unclear and this condition is rarely reported in patients with human immunodeficiency virus (HIV). Here, we report a case of an HIV-infected 73-year old female who experienced hip joint destruction. The patient was diagnosed with HIV in 2012 (at age 68 years) and began continuous treatment with nucleoside reverse transcriptase and protease inhibitors. Twenty-nine months after her HIV diagnosis, the patient experienced osteonecrosis of the right hip and underwent a total hip arthroplasty (THA). Twelve months post right-hip THA, X-ray results showed good outcomes. Eight months later (20 months post THA), however, osteolysis of the left femoral head was detected upon radiological exam and THA of the left hip was performed; chronic inflammation and fibrosis were identified in the resultant biopsy. Favorable results were obtained at 3 months after the second surgery.
