A Case of Metronidazole-Induced Encephalopathy: Atypical Involvement of the Brain on MRI
10.13104/imri.2018.22.3.200
- Author:
Eunjin HWANG
1
;
Suk Ki CHANG
;
Seun Ah LEE
;
Jung Ah CHOI
Author Information
1. Department of Radiology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea. csk1270@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Metronidazole;
White matter abnormality;
Magnetic resonance imaging
- MeSH:
Brain Diseases;
Brain;
Diarrhea;
Magnetic Resonance Imaging;
Metronidazole;
Neurotoxicity Syndromes;
White Matter
- From:Investigative Magnetic Resonance Imaging
2018;22(3):200-203
- CountryRepublic of Korea
- Language:English
-
Abstract:
Metronidazole is an antimicrobial agent widely used for the treatment of anaerobic infection or antibiotics-associated diarrhea. It is generally thought to be safe, but can induce reversible toxic encephalopathy in the case of excessive or cumulative over-dose. Metronidazole-induced encephalopathy generally demonstrates the characteristic features of typical lesion location and bilaterality on magnetic resonance imaging (MRI). We report a case of metronidazole-induced encephalopathy with the involvement of asymmetric white matter. To our knowledge, only a few cases have been reported with respect to white matter lesion characteristics on MRI with diffusion-weighted images.