The Comparative Assessment of Filtering Bleb by Timing of subconjunctival Injection of Mitomycin-C in Glaucoma Filtering Surgery.
- Author:
Dae Won LEE
1
;
Moo Hwan CHANG
;
Jong Hoon LEE
Author Information
1. Department of Ophthalmology, College of Medicine, Dankook University.
- Publication Type:Original Article
- Keywords:
Mitomycin-C;
Preoperative-subconjunctival injection;
Postoperative-subconjunctival injection;
Soaking;
Filtering bleb
- MeSH:
Anterior Chamber;
Blister*;
Filtering Surgery*;
Glaucoma*;
Mitomycin*;
Rabbits
- From:Journal of the Korean Ophthalmological Society
1999;40(2):513-522
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In glaucoma filtering surgery, we conducted subconjunctival injection of Mitomycin-C(MMC) 12 hours before and after surgery, and examined histologic findings of the filtering bleb, and condition of the anterior chamber which ensued after the injection. We divided 15 full-grown rabbits into three groups, and for each group, administered subconjunctivally 0.1cc of 0.002%, 0.004%, and 0.008% MMC, respectively. The subconjunctival injection of MMC before surgery was given to the right eye and post-surgical injection to the left, and we examined the results 1, 2, 4, 7, and 14 days after the administration.In conclusion, subconjunctival injection of MMC 12 hours before glaucoma filtering surgery is shown to be more effective than the injection after the surgery.
