Gelatinous Transformation of Bone Marrow Mimicking Malignant Marrow-Replacing Lesion on Magnetic Resonance Imaging in a Patient without Underlying Devastating Disease
10.13104/imri.2018.22.1.50
- Author:
Joohee LEE
1
;
Yeon Hwa YOO
;
Sarah LEE
;
Hak Sun KIM
;
Sungjun KIM
Author Information
1. Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. agn70@yuhs.ac
- Publication Type:Case Report
- Keywords:
Gelatinous transformation;
Bone marrow;
Magnetic resonance imaging;
Positron emission tomography
- MeSH:
Adipocytes;
Bone Marrow;
Diagnosis;
Gelatin;
Hematologic Neoplasms;
Humans;
Magnetic Resonance Imaging;
Neoplasm Metastasis;
Positron-Emission Tomography;
Spine
- From:Investigative Magnetic Resonance Imaging
2018;22(1):50-55
- CountryRepublic of Korea
- Language:English
-
Abstract:
Gelatinous transformation of bone marrow is characterized by hypoplasia of fat cells with focal loss of hematopoietic cells and deposition of extracellular gelatinous substances. It is known to be associated with devastating underlying diseases that starve bone marrow. Here, we present a case of a patient whose magnetic resonance (MR) imaging findings of vertebral column were interpreted as metastasis or hematologic malignancy, however, the final diagnosis revealed a gelatinous transformation of bone marrow. This is the first report of gelatinous transformation of bone marrow without evidence of underlying devastating disease.
