Effect of Natural Extracts on Oral Care Probiotics Weissella cibaria CMU and Periodontal Pathogens
10.11620/IJOB.2018.43.4.193
- Author:
Ji Eun YEU
1
;
Hyun Jin KIM
;
Mi Sun KANG
Author Information
1. Research Institute, Oradentics Inc., Seoul 04781, Republic of Korea. jieenkang@oradentics.com
- Publication Type:Original Article
- Keywords:
natural extracts;
probiotics;
Weissella cibaria;
antibacterial;
periodontal
- MeSH:
Fusobacterium nucleatum;
Glycyrrhiza;
Microbial Sensitivity Tests;
Morus;
Oral Health;
Porphyromonas gingivalis;
Probiotics;
Propolis;
Tea;
Weissella
- From:International Journal of Oral Biology
2018;43(4):193-200
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of green tea, mulberry leaf, licorice, and propolis, which are reported to have antimicrobial activities, were selected and used in this study. The minimum inhibitory concentrations (MIC) of extracts on periodontal pathogens such as Fusobacterium nucleatum and Porphyromonas gingivalis and their synergy effects with oraCMU by the fractional inhibitory concentrations methods were measured. From the results obtained, all the extracts showed no effect on the growth of oraCMU. Green tea extract showed the best antibacterial activity with MIC of 1.8 mg/ml against both F. nucleatum and P. gingivalis. In addition, green tea extract had a synergistic effect with oraCMU against F. nucleatum. Therefore, these results suggested that green tea extract is available as an additive in oral health food made with oraCMU.
