Single Molecule Method for Molecular Biology
10.11620/IJOB.2018.43.2.053
- Author:
Jeong Hee KIM
1
;
Cherlhyun JEONG
Author Information
1. Department of Oral Biochemistry and Molecular Biology, Kyung Hee University, Seoul 02447, South Korea.
- Publication Type:Review
- Keywords:
single molecule FRET;
single molecule tracking;
super-resolution microscopy;
optical tweezer;
AFM
- MeSH:
Biological Phenomena;
Biological Processes;
Biology;
Methods;
Molecular Biology;
Optical Tweezers;
Spectrum Analysis
- From:International Journal of Oral Biology
2018;43(2):53-59
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In order to understand biological phenomena accurately, single molecule techniques using a physical research approach to molecular interactions have been developed, and are now widely being used to study complex biological processes. In this review, we discuss some of the single molecule methods which are composed of two major parts: single molecule spectroscopy and manipulation. In particular, we explain how these techniques work and introduce the current research which uses them. Finally, we present the oral biology research using the single molecule methods.
