Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature
- Author:
Edris WEDI
1
;
Beatrice ORLANDINI
;
Mark GROMSKI
;
Carlo Felix Maria JUNG
;
Irina TCHOUMAK
;
Stephanie BOUCHER
;
Volker ELLENRIEDER
;
Jürgen HOCHBERGER
Author Information
- Publication Type:Case Report
- Keywords: Colonoscopy; Colorectal neoplasms; Full-thickness resection device; Over-the-scope-clip
- MeSH: Adenocarcinoma; Adenoma; Anastomosis, Surgical; Colon; Colonoscopy; Colorectal Neoplasms; Humans; Immunosuppression; Kidney Transplantation; Lifting; Proctocolitis
- From:Clinical Endoscopy 2018;51(1):103-108
- CountryRepublic of Korea
- Language:English
- Abstract: The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-series describes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications in recently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectal lesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-lifting colonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in a young patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinical success rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrin tumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for either surgical or conventional endoscopic resection strategies.
