Acute Lupus Pneumonitis as Initial Manifestation of Systemic Lupus Erythematosus.
- Author:
Yong Han SUN
1
;
Seon Tae HWANG
;
Byung Wook EUN
;
Jee Eun KIM
;
So Yeon SIM
;
Kang Ho CHO
;
Eell RYOO
;
Deok Young CHOI
;
Dong Woo SON
;
Hann TCHAH
;
In sang JEON
;
Seung Yeon HA
Author Information
1. Department of Pediatrics, Graduate School of Medicine, Gachon University of Medicine and Science, Incheon, Korea. pedsyh@gillhospital.com
- Publication Type:Case Report
- Keywords:
Lupus Erythematosus;
Systemic;
Lung diseases;
Interstitial
- MeSH:
Adolescent;
Adrenal Cortex Hormones;
Anti-Bacterial Agents;
Antibodies;
Biopsy;
Humans;
Lung;
Lung Diseases;
Lupus Erythematosus, Systemic;
Pleural Effusion;
Pneumonia;
Thorax
- From:Pediatric Allergy and Respiratory Disease
2010;20(2):138-142
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report case of a 14-year-old girl with systemic lupus erythematosus who initially presented with acute lupus pneumonitis. She had a 4-week history of exertion for the past 4 weeks, and was transferred from a regional hospital due to abnormality on chest radiographs. Chest radiographs revealed bilateral infiltration and pleural effusion on both lower lung fields. We assumed her to be infected and prescribed antibiotics. The response to antibiotics was ineffective, and viral, bacterial, and mycobacterial cultures were negative. Antinuclear and anti-dsDNA antibodies in serum were positive. The open lung biopsy revealed diffuse alveolar damage. She was diagnosed as having acute lupus pneumonitis in systemic lupus erythematosus and recovered gradually after receiving corticosteroids. Acute lupus pneumonitis may be considered even though interstitial lung involvement in systemic lupus erythematosus is relatively rare in pediatric practice and its diagnosis is difficult.
