Cardiovascular and Neuromuscular Effects of Vecuronium Bromide (Norcuron).
10.4097/kjae.1987.20.3.319
- Author:
Byung Moon HAM
1
;
Jong Deok KIM
Author Information
1. Department of Anesthesiology, College of Medicine, Seoul National University, Korea.
- Publication Type:Original Article
- MeSH:
Halothane;
Heart;
Heart Rate;
Histamine;
Humans;
Neuromuscular Agents*;
Neuromuscular Blockade;
Nitrous Oxide;
Vecuronium Bromide*
- From:Korean Journal of Anesthesiology
1987;20(3):319-325
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We studied the cardiovascular and neuromuscular effects of Norcuron (a new nondepo larizing muscle relaxant) in ASA Claas I patients under halothane and nitrous oxide ane-sthegia. The onset time of Norcuron was 1.06+/-0.27 win, and Clinical duration of action time was 41.49+/-5.53 min and recovery index was 16.38+/-2.30 min and total duration of action time was 67.04 +/-14.42 min.. after volus injection Norcuron 0.1 mg/kg. Norcuron did not change mean arterial presaure, heart rate and histamine secretions and had not arrythmogemic effect on heart rhythm. We conclude that vecuronium bromide (Norcuron) produces a excellent neuromuscular blockade of short duration with little cardiovascular changes and histamine releaae.
