A case of nizatidine-induced immediate hypersensitivity
10.4168/aard.2019.7.2.106
- Author:
Seung Woo PARK
1
;
Yeon Jeong HEO
;
Kyu Sun LEE
;
Jae Woo KWON
Author Information
1. Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea. legent@hanmail.net
- Publication Type:Case Report
- Keywords:
Nizatidine;
Immediate hypersensitivity;
Raniditine;
Histamine H₂ antagonists
- MeSH:
Female;
Gastroesophageal Reflux;
Histamine;
Humans;
Hypersensitivity;
Hypersensitivity, Immediate;
Korea;
Nizatidine;
Peptic Ulcer;
Ranitidine;
Skin;
Stomach;
Urticaria;
Young Adult
- From:Allergy, Asthma & Respiratory Disease
2019;7(2):106-108
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nizatidine is a histamine H₂ receptor antagonist that inhibits stomach acid production and is commonly used in the treatment of peptic ulcer and gastroesophageal reflux. H₂ receptor antagonists are typically well tolerated, and hypersensitivity reactions are rare. A 19-year-old woman developed urticaria 30 minutes after taking a drug containing nizatidine. Allergic reactions to nizatidine were confirmed via skin prick test, which also revealed cross-reactions to ranitidine. We believe that this is the first case report on immediate hypersensitivity to nizatidine in Korea.
