Clinical Outcomes of Elderly Patients with Non ST-Segment Elevation Myocardial Infarction Undergoing Coronary Artery Bypass Surgery
- Author:
Woo Jin KIM
1
;
Myung Ho JEONG
;
Dong Goo KANG
;
Seung Uk LEE
;
Sang Ki CHO
;
Youngkeun AHN
;
Young Jo KIM
;
Chong Jin KIM
;
Myeong Chan CHO
;
Author Information
- Publication Type:Original Article
- Keywords: Myocardial Infaction; Coronary Artery Bypass; Aged
- MeSH: Aged; Coronary Artery Bypass; Coronary Vessels; Death; Follow-Up Studies; Hospital Mortality; Humans; Korea; Myocardial Infarction
- From:Chonnam Medical Journal 2018;54(1):41-47
- CountryRepublic of Korea
- Language:English
- Abstract: The aim of this study is to investigate the clinical outcomes of the elderly patients with Non ST-segment elevation myocardial infarction (NSTEMI) undergoing coronary artery bypass surgery (CABG) compared to non-elderly patients. Patients with NSTEMI and undergoing CABG (n=451) who were registered in the Korea Acute Myocardial Infarction Registry between December 2003 and August 2012 were divided into two groups.; the non-elderly group ( < 75 years, n=327) and the elderly group (≥75 years, n=124). In-hospital mortality was higher in the elderly group (4.9% vs. 11.3%, p=0.015), but cardiac death, myocardial infarction, and major adverse cardiovascular events (MACE) including cardiac death, myocardial infarction, percutaneous revascularization, and redo-CABG after a one-year follow up were not different between the two groups. Predictors of in-hospital mortality in patients with NSTEMI undergoing CABG were left ventricular (LV) dysfunction (ejection fraction ≤40%) [hazard ratio (HR): 2.76, 95% confidence interval (CI): 1.16–6.57, p=0.022] and age (HR: 1.05, 95% CI: 1.01–1.10, p=0.047). So elderly NSTEMI patients should be considered for CABG if appropriate, but careful consideration for surgery is required, especially if the patients have severe LV systolic dysfunction.
