Factors Influencing on the Cognitive Function in Type 2 Diabetics
10.22722/KJPM.2018.26.1.59
- Author:
Dong Hwan GOH
1
;
Jin Sook CHEON
;
Young Sik CHOI
;
Ho Chan KIM
;
Byoung Hoon OH
Author Information
1. Department of Psychiatry, Kosin University College of Medicine, Busan, Korea. cheonjs@kosin.ac.kr
- Publication Type:Original Article
- Keywords:
Type 2 diabetes;
Cognitive dysfunction;
Sex;
Education;
Depression
- MeSH:
Blood Glucose;
Body Mass Index;
Cognition;
Depression;
Diagnosis;
Education;
Fasting;
Humans;
Male
- From:Korean Journal of Psychosomatic Medicine
2018;26(1):59-67
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The aims of this study were to know the frequency and the nature of cognitive dysfunction in type 2 diabetics, and to reveal influencing variables on it. METHODS: From eighty type 2 diabetics (42 males and 38 females), demographic and clinical data were obtained by structured interviews. Cognitive functions were measured using the MMSE-K (Korean Version of the Mini-Mental State Examination) and the Korean Version of the Montreal Cognitive Assessment (MoCA-K) tests. Severity of depression was evaluated by the Korean Version of the Hamilton Depression Rating Scale (K-HDRS). RESULTS: 1) Among eighty type 2 diabetics, 13.75% were below 24 on the MMSE-K, while 38.8% were below 22 on the MoCA-K. 2) The total scores and subtest scores of the MoCA-K including visuospatial/executive, attention, language, delayed recall and orientation were significantly lower in type 2 diabetics with cognitive dysfunction (N=31) than those without cognitive dysfunction (N=49) (p < 0.001, respectively). 3) There were significant difference between type 2 diabetics with and those without cognitive dysfunction in age, education, economic status, body mass index, duration of diabetes, total scores of the K-HDRS, the MMSE-K and the MoCA-K (p < 0.05, respectively). 4) The total scores of the MoCA-K had significant correlation with age, education, body mass index, family history of diabetes, duration of diabetes, total scores of the K-HDRS (p < 0.05, respectively). 5) The risks of cognitive dysfunction in type 2 diabetics were significantly influenced by sex, education, fasting plasma glucose and depression. CONCLUSIONS: The cognitive dysfunction in type 2 diabetics seemed to be related to multiple factors. Therefore, more comprehensive biopsychosocial approaches needed for diagnosis and management of type 2 diabetes.
