Prognostic Significance of Cathepsin-D Expression in Breast Cancer.
10.4048/jkbcs.1998.1.1.45
- Author:
Yong Tae KWON
1
;
Chap Joong JUNG
;
Young Hoon KIM
;
Sae Hun CHO
;
Sang Soom KIM
;
Sook Hee HONG
Author Information
1. Department of Surgery and Patholog1, Dong-A University College of Medicine, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Breast cancer;
Cathepsin-D
- MeSH:
Animals;
Breast Neoplasms*;
Breast*;
DNA;
Estrogens;
Humans;
Mice;
Ploidies
- From:Journal of Korean Breast Cancer Society
1998;1(1):45-53
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mouse monoclonal antibody was used for this study. This study was undertaken to define the prognostic value of the expression of Cathepsin-D in 121 breast cancer patients. The results were as follows: 1) Overall, 53.7% of patients were positive for Cathepsin-D 2) Positive staining did not correlate with age, estrogen receptor status,tumor size, axillary nodal status, tumor stage, menopausal status, pathologic grade, DNA ploidy and S-phase fraction.
