Retinal Nerve Fiber Layer Thickness Measured by Spectral Domain Optical Coherence Tomography in Healthy Koreans
10.3341/jkos.2018.59.6.537
- Author:
Youna CHOI
1
;
Byung Joo CHO
Author Information
1. Department of Ophthalmology, Konkuk University School of Medicine, Seoul, Korea. bjcho@kuh.ac.kr
- Publication Type:Original Article
- Keywords:
Axial length;
Cup-to-disc ratio;
Korean;
Retinal nerve fiber layer;
Spectral domain optical coherence tomography
- MeSH:
Clothing;
Healthy Volunteers;
Nerve Fibers;
Retinaldehyde;
Tomography, Optical Coherence
- From:Journal of the Korean Ophthalmological Society
2018;59(6):537-542
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To determine normal retinal nerve fiber layer (RNFL) thickness by age and to investigate the relationships of the RNFL with clinical variables using spectral domain optical coherence tomography (SD-OCT) in healthy Koreans. METHODS: The peripapillary RNFL thicknesses were measured around the optic disc using consecutive circular B-scans with 3.5 mm diameter and automatically calculated using a SD-OCT. RESULTS: Three hundreds fifty-two eyes of 205 healthy subjects were included in the study and RNFL thickness were measured by SD-OCT. Overall average RNFL thickness was 100.2 ± 10.9 µm, and significantly and negatively correlated with age (r = −0.164, p = 0.002). The overall average RNFL thickness decrease per decade was 0.8 µm (95% confidence interval, −0.3 to −1.3, p = 0.019). Mean RNFL thickness of each quadrant was significantly correlated with axial length except in the superior quadrant. CONCLUSIONS: This study describes the normal RNFL thickness values of Koreans as determined by SD-OCT. Furthermore, age was found to be correlated with normal RNFL thickness, however age-related changes were not uniform across every region.
