Rapid Progression of the Epiretinal Membrane after Intravitreal Aflibercept Injection
10.3341/jkos.2018.59.10.984
- Author:
Ji Min KWON
1
;
Myung Shin LEE
;
Kang Yeun PAK
;
Hyun Woong KIM
Author Information
1. Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. maekbak@gmail.com
- Publication Type:Case Report
- Keywords:
Aflibercept;
Age-related macular degeneration;
Epiretinal membrane
- MeSH:
Aged, 80 and over;
Angiography;
Epiretinal Membrane;
Exudates and Transudates;
Female;
Fluorescein Angiography;
Humans;
Indocyanine Green;
Macular Degeneration;
Macular Edema;
Membranes;
Retinal Hemorrhage;
Retinaldehyde;
Tomography, Optical Coherence;
Visual Acuity;
Vitrectomy
- From:Journal of the Korean Ophthalmological Society
2018;59(10):984-988
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of rapid progression of the epiretinal membrane following intravitreal aflibercept injection in a patient with exudative age-related macular degeneration. CASE SUMMARY: An 82-year-old female presented with a complaint of decreased visual acuity in her left eye for 1 month. The initial best-corrected visual acuity was 0.2 in the left eye. Fundus examination and optical coherence tomography revealed soft drusen with retinal hemorrhage of the macula and a transparent epiretinal membrane in the left eye. Fluorescein angiography and indocyanine green angiography showed retinal angiomatous proliferation (RAP) of the left eye, so intravitreal aflibercept injection was performed. One month after the first injection, intraretinal cystic macular edema decreased, while transparency of the epiretinal membrane decreased and reflectivity and thickness of the membrane increased. After two additional injections of aflibercept, RAP showed improvement, whereas the epiretinal membrane progressed. Visual acuity of the left eye decreased to 0.1 and vitrectomy of the membrane was performed. CONCLUSIONS: Careful observation for potentially rapid progression of epiretinal membrane is needed after intravitreal aflibercept injection in the management of exudate age-related macular degeneration accompanied by epiretinal membrane.
