Survey of Patient Comprehension of Medication Instructions for SGLT2 Inhibitors

Yoko Hirano; Yuki Watase; Yoshitomo O-oka; Kyosuke Tajima; Takaaki Kodawara; Ryoichi Yano; Kyohei Watanabe; Hitoshi Tsukamoto; Nobuyuki Goto

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Survey of Patient Comprehension of Medication Instructions for SGLT2 Inhibitors

VernacularTitle:SGLT2 阻害薬服用患者への服薬指導に対する患者理解度調査
Author: Yoko HIRANO ¹ ; Yuki WATASE ¹ ; Yoshitomo O-OKA ¹ ; Kyosuke TAJIMA ¹ ; Takaaki KODAWARA ¹ ; Ryoichi YANO ¹ ; Kyohei WATANABE ¹ ; Hitoshi TSUKAMOTO ² ; Nobuyuki GOTO ¹
Author Information

1. Department of Pharmacy, University of Fukui Hospital
2. Medical Research Support Center, University of Fukui Hospital
Keywords: SGLT2; adverse drug reactions; patient understanding; medication instruction
From:Japanese Journal of Drug Informatics 2019;20(4):232-237
CountryJapan
Language:Japanese
Abstract: Objective: We evaluated patients’ degree of understanding of the effects and adverse drug reactions of SGLT2 inhibitors.Methods: We targeted 26 patients who were administered SGLT2 inhibitors during hospitalizations between April 2017 and March 2018. The survey was conducted by interviewing the patients using a questionnaire.Results: In total, 14 patients (53. 8%) were able to explain the term “efficacy.” Although 6 patients (23. 1%) understood “dehydration,” there was little understanding of “urinary tract infection” (7.7%) and “rash/erythema” (2 and 0 patients, respectively). In addition, we confirmed the details of the descriptions of adverse reactions caused by SGLT2 inhibitors with pharmacists, and found that 13 patients (50.0%) clearly received an explanation of “dehydration,” only 3 patients received an explanation of “urinary tract infection” (11.5%), and none of them comprehended “rash/erythema.” Overall, the patients’ awareness of the adverse drug reactions of SGLT2 inhibitors was low.Conclusion: Unlike common drugs for diabetes, SGLT2 inhibitors have been attracting attention as protective agents of the heart and kidneys. Therefore, it is expected that prescriptions for SGLT2 will increase in the future. Pharmacists need to explain the effects and adverse drug reactions of SGLT2 inhibitors to the patients as well as make the patients understand the pharmacological mechanisms of action of SGLT2 inhibitors.