Progress in research of bacillus calmette-guerin vaccination and repeated vaccination.
10.3760/cma.j.issn.0254-6450.2018.11.019
- Author:
N N YOU
1
,
2
;
Q LIU
3
;
L M ZHU
3
;
W LU
3
Author Information
1. Institute of Chronic Infectious Disease Prevention and Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
2. Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing 210009, China.
3. Institute of Chronic Infectious Disease Prevention and Control, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
- Publication Type:Review
- Keywords:
Bacillus balmette-guerin;
Repeated vaccination;
Tuberculosis;
Vaccination
- MeSH:
Adolescent;
Adult;
Age Factors;
BCG Vaccine/immunology*;
Child;
Child, Preschool;
Humans;
Time Factors;
Tuberculosis/prevention & control*;
Tuberculosis Vaccines;
Vaccination;
World Health Organization
- From:
Chinese Journal of Epidemiology
2018;39(11):1519-1523
- CountryChina
- Language:Chinese
-
Abstract:
Tuberculosis (TB) is a serious infectious diseases threating human health, bacillus balmette-guerin vaccine (BCG) is the only available TB vaccine now, neonatal vaccination can significantly reduce the incidence and death of tuberculosis. However, due to its limited protection period, one dose vaccination after birth does not have a protective effect for adolescents and adults. Therefore, how to reduce the prevalence of TB in adolescents and adults effectively is essential for TB prevention and control. In this paper, we reviewed the literature from PubMed, CNKI, and Wanfang database to analyze and summarize the characteristics of BCG vaccine, immune effects and immunity endurance, the effects of BCG vaccination and repeated BCG vaccination in adolescents adults and discuse the change of attitude and trends of BCG use in the three documents issued by the World Health Organization on position of BCG.
