A Meta-analysis on the relations between short-term exposure to PM(2.5) and both mortality and related emergency visits in China.
10.3760/cma.j.issn.0254-6450.2018.10.019
- Author:
M LI
1
;
Y WU
;
Y H TIAN
;
G Y CAO
;
S S YAO
;
P AI
;
Z HUANG
;
C HUANG
;
X W WANG
;
Y Y CAO
;
X XIANG
;
J JUAN
;
Y H HU
Author Information
1. Department of Epidemiology and Health Statistics, School of Public Health, Peking University, Beijing 100191, China.
- Publication Type:Review
- Keywords:
Air pollution;
All-cause emergency room visits;
All-cause mortality;
Short-term effects
- MeSH:
Air Pollutants;
Air Pollution/statistics & numerical data*;
China;
Databases, Factual;
Emergency Service, Hospital/statistics & numerical data*;
Environmental Exposure/statistics & numerical data*;
Female;
Humans;
Male;
Particulate Matter/toxicity*;
Time Factors
- From:
Chinese Journal of Epidemiology
2018;39(10):1394-1401
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To carry out a quantitative estimate that related to the effects of short-term exposure to PM(2.5) on all-cause mortality and emergency visits in China by using the systematic review and Meta-analysis. Methods: We selected all the studies published before March 2018 from China National Knowledge Infrastructure, Wanfang database, PubMed and EMBASE and data on relative risk (RR), excess risk (ER) and their 95%CIs: appeared in these papers were extracted. According to the differences in the size or direction (heterogeneity) of the results, we computed summary estimates of the effect values using a random-effect or fixed effect model. We also conducted the subgroup analysis and Meta-analysis to have assessed the selected studies for the evidence of study bias. Results: A total of 33 original studies, indexed in databases, were identified. Among those studies, 39 sets of data on mortality and 4 sets of data on emergency were valid to show that within the daily concentration range from 47.7 to 176.7 μg/m(3), for 10 μg/m(3) increases in PM(2.5) concentrations, it would increase the daily numbers of deaths by 0.49% (95%CI: 0.39%-0.59%) and 0.30% (95%CI: 0.10%-0.51%) for all-cause deaths and all-cause emergency-room visits, respectively. For subgroup analysis, the combined effect of PM(2.5) in causing short-term all-cause deaths in the northern areas (ER=0.42%, 95%CI: 0.30%-0.54%) seemed lower than that in the southern areas (ER=0.63%, 95%CI: 0.44%-0.82%). The combined effect of PM(2.5) concentration below 75 μg/m(3) (ER=0.50%, 95%CI: 0.37%-0.62%) was higher than that of PM(2.5) concentration ≥75 μg/m(3) (ER=0.39%, 95%CI: 0.26%-0.52%). Conclusion: Within the concentration range from 47.7 to 176.7 μg/m(3), short-term exposure to current level of PM(2.5) might increase both the all-cause daily mortality and daily emergency visits in China.
