Effect of famine exposure on the risk of chronic disease in later life among population in Harbin.
10.3760/cma.j.issn.0254-6450.2018.10.005
- Author:
S S JIN
1
,
2
;
B YU
3
;
S C YAN
4
;
W SUN
4
;
X M CUI
4
;
X ZHOU
4
;
L Q YANG
3
;
L X NA
5
;
Y GUO
6
;
Z BIAN
6
;
L M LI
7
;
Z M CHEN
8
Author Information
1. Harbin Medical University, Harbin 150081, China
2. Nangang District, Harbin Center for Disease Control and Prevention, Harbin 150056, China.
3. Nangang District, Harbin Center for Disease Control and Prevention, Harbin 150056, China.
4. Heilongjiang Center for Disease Control, Harbin 150036, China.
5. Harbin Medical University, Harbin 150081, China.
6. Chinese Academy of Medical Sciences, Beijing 100730, China.
7. Peking University School of Public Health, Beijing 100191, China.
8. Nuffield Department of Population Health, Center for Clinical and Epidemiological Studies, University of Oxford, Oxford OX3 7LF, UK.
- Publication Type:Journal Article
- Keywords:
Chronic disease;
Famine exposure;
Retrospective cohort study
- MeSH:
Adolescent;
China/epidemiology*;
Chronic Disease/epidemiology*;
Coronary Disease/epidemiology*;
Diabetes Mellitus/epidemiology*;
Female;
Humans;
Hypertension/epidemiology*;
Obesity/epidemiology*;
Pregnancy;
Prenatal Exposure Delayed Effects/epidemiology*;
Retrospective Studies;
Socioeconomic Factors;
Starvation/epidemiology*
- From:
Chinese Journal of Epidemiology
2018;39(10):1314-1318
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the relations between famine exposure and the risk of chronic diseases as diabetes mellitus, obesity, hypertension, coronary heart disease and stroke in the population of Harbin. Methods: Our data was collected from the baseline survey-the China Kadoorie Biobank project (CKB) in Harbin. Retrospective cohort study design was used. Related risks on chronic diseases including diabetes mellitus, obesity, hypertension, coronary heart disease and stroke, were compared among the famine exposed or non-exposed people, respectively by logistic analysis method. Results: After adjusted for factors as age, sex, physical activity, smoking, alcohol intake, diet, family history of diseases, it appeared that the factor 'famine exposure' had increased the risks of diseases as obesity (OR=1.204, 95%CI: 1.104-1.313, P<0.01), hypertension (OR=1.315, 95%CI: 1.210-1.429, P<0.01) and coronary heart disease (OR=1.495, 95%CI: 1.369-1.632, P<0.01). The lower the age of population being exposed to famine, the greater the risk of the development of all kinds of chronic diseases. Conclusions: Famine exposure appeared a risk factor for obesity, hypertension, and coronary heart disease. It is of great significance to ensure the life-long nutrition of the people, especially in the early and adolescent stages, to prevent obesity, hypertension, and coronary heart disease in their later lives.
