Perspectives of antiviral drugs used on influenza.

Author: Y M WANG ^{1
,

2} ; B CAO
Author Information

1. Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital
2. National Clinical Research Center for Respiratory Diseases, Department of Respiratory Medicine, Capital Medical University, Beijing 100029, China.
Publication Type:Journal Article
Keywords: Antiviral agent; Influenza; Neuraminidase inhibitors; Therapy
MeSH: Antiviral Agents/therapeutic use*; Drug Resistance, Viral; Enzyme Inhibitors/therapeutic use*; Humans; Influenza, Human/drug therapy*; Neuraminidase/therapeutic use*
From: Chinese Journal of Epidemiology 2018;39(8):1051-1059
CountryChina
Language:Chinese
Abstract: Antiviral drugs on influenza are important in the control program of influenza. Options for influenza treatment are currently limited to using the neuraminidase inhibitors (NAIs). Given limited effectiveness of NAIs and related resistance, there remains an urgent need for the development of influenza antiviral drugs that can improve the efficacy and provide low propensity of viral resistance. Several influenza-related antiviral drugs that are currently under the late-stage clinical trials all appear differently in the mechanism of action. It is hoped that when new antiviral drugs are licensed, care and outcomes of severe influenza cases will be improved.