Age-related modification effect on the association between body mass index and the risk of hypertension: A Cohort Study on Chinese people living in the rural areas.
- VernacularTitle:我国成年人群年龄对体质指数与高血压发病风险的修饰效应
- Author:
D D ZHANG
1
;
X J LIU
1
;
B Y WANG
1
;
Y C REN
1
;
Y ZHAO
1
;
F Y LIU
2
;
D C LIU
1
;
C CHENG
1
;
X CHEN
1
;
L L LIU
1
;
Q G ZHOU
2
;
Q H XU
3
;
Y H XIONG
3
;
J L LIU
3
;
Z Y YOU
3
;
M ZHANG
2
;
D S HU
1
Author Information
- Publication Type:Journal Article
- Keywords: Age; Body mass index; Cohort; Hypertension; Modification
- MeSH: Adolescent; Age Factors; Aged; Asian People/statistics & numerical data*; Body Mass Index; Cohort Studies; Female; Follow-Up Studies; Humans; Hypertension/ethnology*; Incidence; Logistic Models; Male; Middle Aged; Risk Factors; Rural Population
- From: Chinese Journal of Epidemiology 2018;39(6):765-769
- CountryChina
- Language:Chinese
- Abstract: Objective: To study the modification effect of age on the association between body mass index and the risk of hypertension. Methods: People age ≥18 years old were selected by clusters, from a rural area of Henan province. In total, 20 194 people were recruited at baseline during 2007 and 2008, and the follow-up study was completed from 2013 to 2014. Logistic regression model was used to assess the risk of incident hypertension by baseline BMI and age-specific BMI. Results: During the 6-year follow-up period, 1 950 hypertensive persons were detected, including 784 men and 1 166 women, with cumulative incidence rates as 19.96%, 20.51%, and 19.61%, respectively. Compared with those whose BMI<22 kg/m(2), the RRs of hypertension were 1.09 (0.93-1.27), 1.17 (1.01-1.37), 1.34 (1.14-1.58) and 1.31 (1.09-1.56) for participants with BMI as 22-, 24-, 26- and ≥28 kg/m(2), respectively. In young and middle-aged populations, the risk of hypertension gradually increased with the rise of BMI (trend P<0.05). However, in the elderly, the increasing trend on the risk of hypertension risk was not as significantly obvious (trend P>0.05). Conclusion: The effect of BMI on the incidence of hypertension seemed to depend on age. Our findings suggested that a weight reduction program would be more effective on young or middle-aged populations, to prevent the development of hypertension.
