Torsade de Points Ventricular Tachycardia Associated with Piprinhydrinate(Diphenylpyraline, Plokon(R)).
10.4070/kcj.1996.26.1.143
- Author:
Young Cheoul DOO
;
Tae Ho HAHN
;
Dae Kyung KIM
;
Byung Dong CHO
;
Soon Hee KOH
;
Kyoo Rok HAN
;
Dong Jin OH
;
Kyu Hyung RYU
;
Chong Yun RIM
;
Young Bahk KOH
;
Young LEE
- Publication Type:Case Report
- Keywords:
Torsade de points;
Antihistamine;
Ventricular Tachycardia;
Piprinhydrinate
- MeSH:
Antipsychotic Agents;
Dizziness;
Ethanolamine;
Histamine Antagonists;
Syncope;
Tachycardia, Ventricular*;
Terfenadine
- From:Korean Circulation Journal
1996;26(1):143-148
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Torsade de Points is unique polymorphic ventricular tachycardia associated with QT interval prolongation. The mechanism of Torsade de Points was not defined exactly but triggered activity associated with afterdepolarization and/or dispersion of repolarization were known possible explanation. Torsade de points is most often induced by various drugs such as antiarrythmic agents, antipsychotic agents, antibiotis, and antihistamines. Astemizole(Hismanal(R)) and Terfenadine among antihistamines are reported that cause leading to a Torsade de Points. We experienced the case of Torsade de Points which was induced with Piprinhydrinate(Diphenylpyraline, Plokon(R)), antihistamine of ethanolamine derivatives, expressed recurrent syncope and dizziness in a young lady.
