Realization of design regarding experimental research in the clinical real-world research.
10.3760/cma.j.issn.0254-6450.2018.04.027
- VernacularTitle:临床真实世界研究中的实验性研究设计
- Author:
Q HE
1
;
J P SHI
2
,
3
Author Information
1. Department of Clinical Epidemiology and Evidence-based Medicine, the First Affiliated Hospital.
2. Department of Clinical Epidemiology and Evidence-based Medicine, the First Affiliated Hospital
3. Center of Evidence Based Medicine of Liaoning Province, China Medical University, 110001 Shenyang, China.
- Publication Type:Journal Article
- Keywords:
Experimental research;
Explanatory randomized controlled trial;
Pragmatic randomized controlled trials;
Real world study;
Registry-based randomized controlled trials
- MeSH:
Clinical Studies as Topic;
Humans;
Registries;
Research Design
- From:
Chinese Journal of Epidemiology
2018;39(4):519-523
- CountryChina
- Language:Chinese
-
Abstract:
Real world study (RWS), a further verification and supplement for explanatory randomized controlled trial to evaluate the effectiveness of intervention measures in real clinical environment, has increasingly become the focus in the field of research on medical and health care services. However, some people mistakenly equate real world study with observational research, and argue that intervention and randomization cannot be carried out in real world study. In fact, both observational and experimental design are the basic designs in real world study, while the latter usually refers to pragmatic randomized controlled trial and registry-based randomized controlled trial. Other nonrandomized controlled and adaptive designs can also be adopted in the RWS.
