Differences on geographic distribution of rabies virus lineages in China.
10.3760/cma.j.issn.0254-6450.2018.04.021
- VernacularTitle:中国不同地区狂犬病病毒种群分布的差异
- Author:
Q WANG
1
;
M L LI
2
;
Y CHEN
3
;
B WANG
3
;
X Y TAO
1
;
W Y ZHU
1
Author Information
1. National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
2. Department of Pathology, Shenzhen People's Hospital, Shenzhen 518020, China.
3. Shenyang Center for Disease Control and Prevention, Shenyang 110031, China.
- Publication Type:Journal Article
- Keywords:
Distribution;
Epidemic;
Lineage;
Rabies;
Rabies virus
- MeSH:
Animals;
China/epidemiology*;
Humans;
Phylogeny;
Rabies/epidemiology*;
Rabies virus;
Tibet
- From:
Chinese Journal of Epidemiology
2018;39(4):491-494
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the lineages of rabies virus and the epidemic characteristics in different provincial populations of China, to provide information for the development of control and prevention measures in each respective provinces. Methods: Full length N and G genes and full-genome of epidemic strains of rabies virus collected in China were downloaded from GenBank and combined with newly sequenced strains by our lab. Each strain was classified under six lineages of China rabies by constructing phylogenetic trees based on the N or G sequences. Numbers of strains and lineages in each province were counted and compared. Results: Six lineages (China Ⅰ-Ⅵ) were prevalent in China, with 4 found in Yunnan and Hunan. In 6 provinces, including Henan and Fujian, 3 lineages were found. In 8 provinces, including Shanghai and Jiangxi, 2 lineages were found Only 1 lineage, were found in Beijing, Tianjin and other 12 provinces. the China Ⅰ, was the dominant one in 25 provinces. In recent years, China Ⅲ had been found in wild animals and spread over livestock in Inner Mongolia and Xinjiang areas. Qinghai and Tibet had been influenced by China Ⅳ, which also been found in wild animals of Inner Mongolia and Heilongjiang. Conclusion: There had been obvious differences in lineages and strain numbers of rabies virus identified in different provinces in China.
