Dynamic variations of BMI and influencing factors among HIV/AIDS patients receiving highly active antiretroviral therapy in Liuzhou, Guangxi Zhuang Autonomous Region, 2013-2014.
10.3760/cma.j.issn.0254-6450.2018.04.020
- VernacularTitle:广西壮族自治区柳州市2013-2014年HIV/AIDS抗病毒治疗后BMI变化及相关因素分析
- Author:
H H CHEN
1
;
B T FU
2
;
Q Y ZHU
1
;
H X LU
1
;
L H LUO
1
;
L CHEN
1
;
X H LIU
1
;
X J ZHOU
1
;
J H HUANG
1
;
X X FENG
3
;
G S SHAN
3
;
Z Y SHEN
1
Author Information
1. Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, China.
2. Luzhai Center for Disease Control and Prevention, Luzhai 545600, China.
3. Liuzhou Center for Disease Control and Prevention, Liuzhou 455001, China.
- Publication Type:Journal Article
- Keywords:
Acquired immune deficiency syndrome;
Antiretroviral therapy;
Body mass index
- MeSH:
Acquired Immunodeficiency Syndrome;
Antiretroviral Therapy, Highly Active;
Body Mass Index;
CD4 Lymphocyte Count;
China/epidemiology*;
HIV Infections/drug therapy*;
Humans;
Linear Models;
Marital Status;
Nutritional Status;
T-Lymphocytes
- From:
Chinese Journal of Epidemiology
2018;39(4):487-490
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To understand the dynamic variation of BMI and influencing factors among HIV/AIDS patients receiving highly active anti-retroviral therapy (HAART) in Liuzhou, Guangxi Zhuang Autonomous Region (Guangxi). Methods: HIV/AIDS patients receiving HAART for the first time since 1 January 2013 were selected. Data on BMI was analyzed among patients receiving HAART at baseline,6 months and 12 months after treatment. By using the general linear model repeated measures of analysis of variance, BMI dynamic variations and influencing factors were described and analyzed. Results: The average BMI of 2 871 patients at baseline, 6th months and 12th months appeared as (20.65±3.32), (20.87±3.22) and (21.18±3.20), respectively, with differences all statistically significant (F=18.86, P<0.001). BMI were increasing over time with treatments (F=37.25, P<0.001). Main influencing factors were noticed as: age, sex, marital status, baseline data of CD(4)(+)T cells and the WHO classification on clinical stages. Conclusions: Higher proportion of BMI malnutrition counts was seen among patients before receiving HAART in Liuzhou. BMI of the patients that were on HAART seemed being influenced by many factors. It is necessary to select appropriate treatment protocols on different patients so as to improve the nutritional status of the patients.