Effect of health literacy and exercise-focused interventions on glycemic control in patients with type 2 diabetes in China.
10.3760/cma.j.issn.0254-6450.2018.03.021
- Author:
X N LIU
1
;
Q H XIA
2
;
H FANG
3
;
R LI
4
;
Y Y CHEN
5
;
Y J YAN
3
;
P ZHOU
2
;
B D YAO
3
;
Y JIANG
2
;
W G ROTHMAN
6
;
Wanghong XU
1
Author Information
1. Department of Epidemiology, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, Shanghai 200032, China.
2. Department of Chronic Diseases Control, Changning District Center for Disease Control and Prevention, Shanghai 200336, China.
3. Department of Chronic Diseases Control, Minhang District Center for Disease Control and Prevention, Shanghai 201101, China.
4. Department of Diabetes Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
5. Department of Hospital Management, School of Public Health, Key Laboratory of Health TechnologyAssessment, Ministry of Health, Fudan University, Shanghai 200032, China.
6. Department of Internal Medicine and Pediatrics and Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.
- Publication Type:Randomized Controlled Trial
- Keywords:
Diabetes, type 2;
Exercise;
Health literacy;
Hemoglobin A1c;
Intervention
- MeSH:
Blood Glucose/analysis*;
China;
Diabetes Mellitus, Type 2/therapy*;
Disease Management;
Exercise;
Follow-Up Studies;
Glycated Hemoglobin/analysis*;
Health Literacy;
Humans;
Patient Education as Topic;
Self Care;
Surveys and Questionnaires;
Treatment Outcome
- From:
Chinese Journal of Epidemiology
2018;39(3):357-362
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the effect of health literacy and exercise-focused interventions on glycemic control in patients with type 2 diabetes (T2DM) in China. Methods: In this cluster randomized controlled trial, a total of 799 T2DM patients with most recent hemoglobin A1c (HbA1c) ≥ 7.5% (or fasting plasma glucose level ≥10 mmol/L) were recruited from 8 communities in Minhang and Changning districts of Shanghai, and randomized into a health literacy intervention group, an exercise intervention group, a comprehensive intervention group and a control group. After baseline survey and examination, a one-year intervention and 3 times (at 3(rd), 6(th), and 12(th) month) follow-up surveys were conducted. Results: The follow-up rates for all the subjects were 99.4%, 98.4% and 95.2%, respectively, at 3(rd), 6(th) and 12(th) month. Patients in intervention groups were more likely to achieve a goal HbA1c level (HbA1c <7.0%) than those in control group, with the highest glycemic control rate (25.3%) observed in comprehensive intervention group at 3(rd) month and then in exercise intervention group (25.3% and 34.6%) respectively, at 6(th) month and 12(th) month. The average levels of HbA1c in three intervention groups were lower at each follow-up time point than those at baseline survey. However, the decreases in HbA1c were obvious only at 6(th) month (P<0.001), with ls-mean (95%CI) of -0.48% (-0.71%, -0.25%), -0.33% (-0.55%, -0.11%) and -0.70% (-0.92%, -0.48%), respectively, in comprehensive, health literacy and exercise intervention groups, but it increased slightly by 0.03% (-0.19%, 0.25%) in control group. Compared with control group, the interventions were significantly associated with the decrease of HbA1c level, with the most improvement observed in comprehensive group (β=-0.47, 95% CI: -0.73, -0.20) at 3(rd) month, and in exercise intervention group at 6(th) month (β=-0.73, 95%CI: -0.98, -0.47) and at 12(th) month (β=-0.75, 95%CI: -1.05, -0.45) of follow-up. Stratified analyses showed that patients with lower health literacy level could benefit from any intervention, while those with higher numeracy skill benefited more from exercise intervention. Conclusion: Both health literacy and exercise-focused interventions may decrease HbA1c level in patients with T2DM, which would be helpful in reducing the risks of complications and deaths in diabetes patients.
