Progress on influencing factors regarding the neonatal group B streptococcal infectious diseases.
10.3760/cma.j.issn.0254-6450.2018.02.022
- VernacularTitle:新生儿B族链球菌感染相关疾病影响因素的研究进展
- Author:
X HONG
1
,
2
;
H YU
3
;
B WANG
1
,
2
Author Information
1. Department of Epidemiology and Health Statistics, School of Public Health, Southeast University
2. Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Nanjing 210009, China.
3. Department of Obstetrics, Southeast University Affiliated Zhongda Hospital, Nanjing 210009, China.
- Publication Type:Journal Article
- Keywords:
Group B streptococcus;
Infection;
Neonatal;
Risk factor
- MeSH:
Female;
Humans;
Infant, Newborn;
Infectious Disease Transmission, Vertical;
Pregnancy;
Pregnancy Complications, Infectious/urine*;
Premature Birth;
Streptococcal Infections/urine*;
Streptococcus agalactiae/isolation & purification*;
Vagina/microbiology*
- From:
Chinese Journal of Epidemiology
2018;39(2):249-252
- CountryChina
- Language:Chinese
-
Abstract:
Group B streptococcus (GBS) is one of the severe pathogenic bacteria during the perinatal period, both on pregnant women and newborns. GBS infection may lead to pneumonia, septicemia, meningitis or other severe disease, even death in neonates. Although only 1%-2% infections will develop into GBS disease among the neonates, the etiological mechanism of which is worth researching. This review summarizes the possible factors related to GBS infection or occurrence of the disease, including the risk in gestation period (for example, colonization of GBS on vagina of pregnant women, preterm birth or premature rupture of fetal membranes and so on), related pathogens (bacteria strains, loads or virulence), immune level (inflammatory factor or neutralizing anticytokine auto-Abs), gene defect or primary immunodeficiencies of the hosts.
