Prevalence and related factors of HIV/HBV coinfection among HIV/AIDS patients
10.3760/cma.j.issn.0254-6450.2017.12.008
- VernacularTitle:艾滋病病毒感染者合并乙型肝炎病毒感染现状及其相关因素研究
- Author:
Dan FENG
1
;
Tian YAO
;
Yanpeng CHENG
;
Minghu PAN
;
Chunxia LI
;
Jun WANG
;
Yongliang FENG
;
Jing SHI
;
Honglang HUANG
;
Hongyan LU
;
Guanghua LAN
;
Suping WANG
;
Yawei ZHANG
Author Information
1. 山西医科大学公共卫生学院流行病学教研室
- Keywords:
HIV;
HBV;
Coinfection;
Related factors
- From:
Chinese Journal of Epidemiology
2017;38(12):1624-1628
- CountryChina
- Language:Chinese
-
Abstract:
Objective To reveal the prevalence and the related factors of hepatitis B (HepB) virus infection among HIV/AIDS patients.Methods We conducted a cross-sectional study in two HIV clinics,affiliated to local Centers of Disease Control and Prevention in Guangxi Zhuang Autonomous Regional.A face-to-face interview,with questionnaire was conducted to collect information on socio-demographic characteristics,drug use,and sexual behavior.Blood samples were used to test HBsAg.x2 test or Fisher's exact test and unconditional logistic regression models were used to identify the influencing factors.Results The prevalence of HBV and HIV co-infection was 13.85% (113/816).Results from multivariate logistic regression analyses showed that age (25-45),family history of HBV and history of HepB vaccination were independent influencing factors for HBV and HIV coinfection,with OR (95% CI) as 1.738 (1.031-2.931),2.898 (1.678-5.005) and 1.744 (1.052-2.892),respectively.Conclusion The prevalence of HBV among HIV/AIDS patients was significantly higher than that in general population.HIV/AIDS patients aged between 25 and 45 and with family history of HBV were more likely to be infected with HBV,while HepB vaccination was associated with the reduction of HIV/HBV coinfection.Specific comprehensive prevention and treatment programs on HIV/AIDS patients need to be set up.