Gender differences in stressful life events and depression in Chinese adults aged 30-79 years
10.3760/cma.j.issn.0254-6450.2017.11.002
- VernacularTitle:中国30~79岁成年人负性生活事件与抑郁关联的性别差异研究
- Author:
Man WU
1
;
Jiachen LI
;
Canqing YU
;
Yiping CHEN
;
Jun LYU
;
Yu GUO
;
Zheng BIAN
;
Yunlong TAN
;
Pei PEI
;
Junshi CHEN
;
Zhengming CHEN
;
Liming LI
Author Information
1. 100191,北京大学公共卫生学院流行病与卫生统计学系
- Keywords:
Depression;
Stressful life events;
Gender difference;
Cross-sectional studies
- From:Chinese Journal of Epidemiology
2017;38(11):1449-1453
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate gender specific differences in the association between stressful life events (SLEs) and depression in Chinese adults aged 30-79 years. Methods In the baseline survey during 2004-2008, the China Kadoorie Biobank (CKB) recruited 512891 men and women aged 30-79 years from 10 areas of China. Detailed information on SLEs, including demographic and socio-economic status, smoking, alcohol drinking and history of chronic disease, as well as depression symptoms and major depressive episodes (MDEs) in preceding 12 months, was collected by using standardized questionnaire. Multinomial logistic regression model was employed to estimate the relative risk ratio (RRR) and 95%CI of SLEs (3 categories, 10 items) on depression and the dose-response relationship between the number of SLEs experienced and depression. The interactions between gender and SLEs on depression were examined with likelihood ratio test. Results Among the 512891 participants, 35085 (6.8%) reported family-related events, 5972 (1.2%) reported finance-related events, and 4453 (0.9%) reported other stressful life events. Females had a higher occurrence of family-related events, while males had a higher occurrence of finance-related and other events (all P-value <0.001). After adjusted for potential confounders, SLEs were significantly associated with MDEs (RRR=11.99, 95%CI: 10.49-13.71 for males; RRR=14.15, 95%CI: 12.97-15.43 for females), and with depressive symptoms (RRR=7.43, 95%CI:6.94-7.95 for males;RRR=8.30, 95%CI: 7.91-8.72 for females). And the associations were stronger in females than in males (P for interaction=0.049). In the three categories of SLEs, family-related events showed stronger association in female (P for interaction<0.001), while no gender specific differences were observed for the other two categories (all P-value>0.05). Furthermore, the effect of the number of SLEs experienced increased in a dose-response manner on depressive symptoms and MDEs for both genders, but no gender specific differences were found. Conclusions The gender modifies the association between stressful life events and depression in Chinese adults, and women experienced family-related events have a greater risk of depression. The more the stressful events experienced, the more likely to have depression.
