A twin study of genetic and environmental influences on relationship between attention deficit and anxiety/depression in children and adolescents

VernacularTitle:儿童青少年注意问题和焦虑/抑郁相关遗传与环境因素影响的双生子研究
Author: Shangshang WANG ^{1
,

2} ; Tianjiao CHEN ; Chengye JI
Author Information

1. 100191 北京大学公共卫生学院/北京大学儿童青少年卫生研究所
2. 100007 北京市东城区卫生和计划生育委员会
Keywords: Attention deficit; Anxiety/depression; Genetic and environmental factors; Twin; Children and adolescents
From: Chinese Journal of Epidemiology 2017;38(9):1183-1186
CountryChina
Language:Chinese
Abstract: Objective To understand the genetic and environmental influences on the relationship between attention deficit and anxiety/depression in children and adolescents.Methods A total of 1 062 same-sex twins aged 6-18 years were included in this study.A parent-rated child behavior checklist (CBCL) was used in the assessment.Software Mx was used to fit the univariate model of structural equation.The relationship between attention deficit and anxiety/depression was analyzed through bivariate genetic modeling.Results The genetic factor had influence on the relationship between attention deficit and anxiety/depression (rg=0.48).Shared and non-shared environmental correlation scores of attention deficit and anxiety/depression were 0.86 and 0.14 respectively.Conclusion Common genetic and shared environmental influences can explain the relationship between attention deficit and anxiety/depression in children and adolescents.