Relationship between pesticide exposure and adverse pregnancy outcomes among reproductive couples in rural areas of China
10.3760/cma.j.issn.0254-6450.2017.06.008
- VernacularTitle:农药接触与不良妊娠结局:中国农村地区的一项前瞻性队列研究
- Author:
Yimin QU
1
;
Shi CHEN
;
Juanjuan LI
;
Rongrong JIN
;
Hui PAN
;
Yu JIANG
Author Information
1. 中国医学科学院北京协和医学院公共卫生学院
- Keywords:
Pesticide exposure;
Adverse pregnancy outcomes;
Cohort study
- From:
Chinese Journal of Epidemiology
2017;38(6):732-736
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the association between pesticide exposure and adverse pregnancy outcomes in women from the rural areas of China.Methods Data of "National Free Preconception Health Examination Project (NFPHEP)" from January 2010 to December 2012 was used for analysis.A total of 248 501 families that were planning to deliver a baby in the next 6 months were enrolled.Data on paternal exposure to pesticides before or during pregnancy was collected through questionnaires,with related outcomes on pregnancy recorded by doctors.Results Among all the 248 501 participants,1 806 (0.74％) women and 2 653 (1.09％) men reported to have been exposed to pesticide before pregnancy,with 505 (0.21％) reported of having been exposed to pesticide during the period of pregnancy.Maternal exposure to pesticide was found a risk factor related to stillbirth (OR=3.37,95 ％ CI:2.05-5.55),peculiar smell pregnancy (OR =3.17,95％CI:1.18-8.55) and low birth weight (OR=7.56,95％ CI:5.36-10.66).Paternal exposure to pesticide was also found related to miscarriage (OR=1.37,95％ CI:1.03-1.80),low birth weight (OR=3.65,95％ CI:1.51-8.84),or giant infant (OR?=0.64,95％ CI:0.44-0.93).Maternal exposure to pesticide during pregnancy appeared a risk factor on miscarriage (OR=4.65,95％ CI:3.47-6.24).Other adverse outcomes on pregnancy would include premature birth and high birth weight.Conclusion Parental pesticide exposure appeared a risk factor on stillbirth,peculiar smell pregnancy,low birth weight and miscarriage.
