Compliancy of pre-exposure prophylaxis for HIV infection in men who have sex with men in Chengdu
10.3760/cma.j.issn.0254-6450.2017.05.017
- VernacularTitle:成都市男男性行为人群艾滋病暴露前预防用药服药依从性分析
- Author:
Jiayue XU
1
;
Yuchan MOU
;
Yuanlin MA
;
Juying ZHANG
Author Information
1. 四川大学华西公共卫生学院流行病与统计学系
- Keywords:
Men who have sex with men;
AIDS;
Pre-exposure prophylaxis;
Compliancy
- From:
Chinese Journal of Epidemiology
2017;38(5):643-645
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the compliancy of HIV pre-exposure prophylaxis (PREP) in men who have sex with men (MSM) in Chengdu,Sichuan province,and explore the influencing factors.Methods From 1 July 2013 to 30 September 2015,a random,open,multi-center and parallel control intervention study was conducted in 328 MSM enrolled by non-probability sampling in Chengdu.The MSM were divided into 3 groups randomly,i.e.daily group,intermittent group (before and after exposure) and control group.Clinical follow-up and questionnaire survey were carried out every 3 months.Their PrEP compliances were evaluated respectively and multivariate logistic regression analysis was conducted to identify the related factors.Results A total of 141 MSM were surveyed,in whom 59(41.8％) had good PrEP compliancy.The PrEP compliancy rate was 69.0％ in daily group,higher than that in intermittent group (14.3％),the difference had significance (x2=45.29,P＜0.001).Multivariate logistic analysis indicated that type of PrEP was the influencing factors of PrEP compliancy.Compared with daily group,the intermittent group had worse PrEP compliancy (OR=0.07,95％CI:0.03-0.16).Conclusion The PrEP compliance of the MSM in this study was poor,the compliancy would be influenced by the type of PREP.
